A review of the existing literature on saw palmetto and hair loss
There is not a lot of research available on the efficacy of saw palmetto when it comes to reducing or preventing hair loss. However, it can certainly be said that the botanical extract has gained popularity in recent years. So, what do existing studies show?
A study in 1998 revealed that long-term treatment with Serenoa repens showed a significant decrease in DHT in men with benign prostatic hyperplasia (BHP), confirming its capacity to inhibit 5-alpha reductase [11]. It states that these biochemical effects are similar to those obtained with Finasteride – a drug that’s also used in reducing hair loss in men.
In essence, it is a natural product that can replicate the synthetic ingredients in Finasteride or similar prescription medications to some limited extent. However, the effects of saw palmetto are significantly smaller than the effects achieved with Finasteride [6].
Later, a 2016 study also showed that saw palmetto inhibits the activity of the enzyme linked to BHP (and therefore male androgenetic alopecia hair loss) and that the amount of the extract that is required is comparatively low [12]. Whilst this showed its effectiveness on prostate health, a 2018 study also showed its efficacy where Serenoa repens extract promoted hair regeneration and repair of hair loss in mice [13].
A systematic review of saw palmetto (Natural Hair Supplement: Friend or Foe? Saw Palmetto, a Systematic Review in Alopecia) [14] published in 2020 showed that the extract improved the overall hair quality by 60%. There was also a 27% improvement in the total number of hairs and an increased density in over 83% of patients. What’s more, hair loss was stabilised in 52% of patients.
This review also showed that saw palmetto was tolerated well by patients without any significant adverse effects and summarised that it may be a viable treatment option for those with telogen effluvium, self-perceived hair thinning and indeed AGA.
Whilst research is not overly plentiful, studies so far show that saw palmetto (Serenoa repens) certainly has a lot of promise as a hair loss remedy. However, when looking at its efficacy, other research does not seem to back up its effects. Two large studies using different saw palmetto preparations found that it was no more effective than a placebo when treating symptoms of BHP [15].
Whilst these studies weren’t testing the effects on hair loss specifically, they do call into question saw palmetto’s efficacy where reducing DHT activity is concerned.