How would hair cloning work?
There are 3 main ways in which hair cloning can theoretically be performed to good results in treating androgenetic alopecia in a human patient [3]. They all start with harvesting some healthy hair follicles from the back of the patient’s scalp, then one or more of the following procedures may be applied:
Method #1
Stem cells are harvested from healthy hair follicles and multiplied in vitro. They are chosen because their plasticity allows them to develop into trichogenic cells, which promote hair production and growth.
These cells are then implanted in the problem areas of the scalp (e.g. a bald spot on the crown, a widening midline parting or a receding hairline). There, they are incorporated by the hair follicles affected by androgenetic alopecia, reversing their miniaturisation and rendering them immune to androgenetic alopecia.
Method #2
Stem cells or follicular fragments are harvested and multiplied in vitro. Then, they are implanted in scalp areas where hair follicles have been destroyed or aren’t sufficient, growing into brand-new ones.
These new healthy follicles would not be affected by androgen hormones such as dihydrotestosterone (DHT) and, thus, would be free from the effects of pattern baldness.
Method #3
Stem cells are multiplied and grown in vitro to the point where they develop into functional hair follicles that develop budding hair (proto-hairs). They are implanted in the balding area of the scalp through a procedure very similar to a regular hair transplant.
These small hairs are helped to grow in the right direction and integrate into the skin by biodegradable microscopic support structures (scaffolding) implanted alongside them.