Immunotherapy
Immunotherapy for hair loss is a type of treatment which is normally used for autoimmune conditions, such as alopecia areata. It involves applying certain irritant substances topically to the scalp, to alter your immune system response [16]. Some of the most common forms of immunotherapy for hair loss involve JAK inhibitors, medications which play a role in reducing the inflammatory signals which contribute to autoimmune reactions [17].
How does immunotherapy work?
The chemicals added to your scalp irritate it, provoking a mild allergic reaction. This creates controlled inflammation, in an attempt to determine the immune system to start protecting your hair follicles from the allergens instead of attacking them [16].
What conditions can immunotherapy treat
Immunotherapy treatment for hair loss is most commonly used in the treatment of alopecia areata, but may also be effective in treating other inflammatory conditions, such as atopic dermatitis (eczema).
Who is a good candidate for immunotherapy?
- Immunotherapy is usually prescribed to patients with localized hair loss that has not responded to corticosteroid treatments
- It is recommended to healthy patients, with no history of adverse effects to medications which alter your immune response
- Some candidates may already use JAK inhibitors to treat conditions like Crohn’s disease and any related hair loss
- Immunotherapy for hair loss is not recommended for pregnant or breastfeeding women or people with severe allergies
What are the risks of immunotherapy?
Topical immunotherapy can produce some unwanted side effects, such as [16]:
- Persistent dermatitis
- Generalized eczema
- Enlargement of the lymph nodes in your neck
- Blistering
- Scalp rash
- Yellowing of grey hair
- Whitening of the scalp
- Triggering a flare-up of your autoimmune condition
Can you get immunotherapy for hair loss on the NHS
No, you can not get immunotherapy for hair loss on the NHS. If you are a good candidate, you may be recommended this kind of treatment at a private hair clinic.